Long-Term Social Supports Needed After Onset of Psychosis
New data on the effects of social support after early onset of psychosis suggests that patients with intense social support function better than those without such help, but than once supports are removed the effects diminish.
Pennsylvania Foster Kids Prescribed Too Many Psychotropic Drugs
Amid growing criticism about the over-prescription of psychotropic medication in foster care, Pennsylvania commissioned PolicyLab to conduct an analysis of the use of psychiatric drugs among all of the state’s Medicaid-enrolled children. The report, released in June, found that the rate of psychotropic prescriptions among youth in Medicaid and foster care was higher than previously reported.
Meta-Analysis Ties Gray Matter Loss to Antipsychotic Dose
Antipsychotics are currently the predominant treatment for individuals diagnosed with schizophrenia, but there is an accumulating body of research that links the use of these drugs to structural abnormalities in the brain. A recent meta-analysis suggests that gray matter loss in the brain may depend on the dose and class of the antipsychotic.
Antipsychotics Prescribed Off-Label for Challenging Behaviors
Antipsychotics are being prescribed to people who may have challenging behaviors but no mental disorder, according to new research published in this month’s issue of BMJ. “Excessive use of psychotropic drugs has individual and systemic implications,” the researchers write. “Antipsychotics, in particular, are associated with several adverse side effects that can impair quality of life and lead to deleterious health outcomes.”
“Antipsychotic Use in Youth Without Psychosis: A Double-edged Sword”
This month’s issue of JAMA Psychiatry ran an editorial commenting on recent research revealing that the majority of youth prescribed antipsychotics have not been diagnosed with a mental disorder.
Members of FDA Advisory Committee Offer Perspectives on Flibanserin Approval in JAMA
In the September issue of The Journal of the American Medical Association (JAMA) three FDA advisory committee members describe the convergence of factors that made the committee’s recommendation to approve flibanserin especially challenging and politically charged.
“Janssen Accused of Withholding Data on Risperdal Side Effect in Autism”
MedPageToday reports that Janssen Pharmaceuticals omitted data from a 2003 study that connected Risperdal with serious side effects. Janssen was previously sued by the FDA for marketing Risperdal for off-label uses and settled for $2.2 billion in 2013. Earlier this year, a man with autism was awarded $2.5 million after growing breasts while on Risperdal. According to MedPage, documents from this latest case reveal missing data tables from a 2003 study “designed to ferret out potential adverse effects of long-term risperidone use.” The missing tables were related to elevated prolactin levels and side effects, including gynecomastia in men.
Harvard’s Madras Critiques University of Pittsburgh Marijuana Study
Bertha Madras, professor of psychobiology at Harvard Medical School, has printed a critique listing 20 flaws to a recent study finding no differences in physical or mental health problems between users and non-users of marijuana.
Failure to Follow New Research Guidelines Problem for Top Psychiatry Journals
Despite updated standards requiring preregistration of clinical trials aimed at improving transparency, most studies published in the top-5 psychiatry journals from 2009 to 2013 do not meet the new guidelines, according to an analysis published in PloS one.
FDA Approves Controversial “Pink Viagra”
On Tuesday, the U.S. Food and Drug Administration (FDA) approved Flibanserin (Addyi) to treat low sexual desire in women despite concerns about the drug's limited efficacy and doubts over its clinical relevance. That the drug is being called the "pink Viagra" can be misleading as Viagra treats erectile dysfunction by improving blood flow while Flibanserin targets the brain, and must be taken daily.
Omega-3 Fatty Acids May Help Prevent Transition to Psychosis
“When people with early-stage symptoms took omega-3 supplements for three months, they had much lower rates of progression than those who did not,” according to research out of Australia covered in this month’s issue of the New Scientist.
Seniors More Likely to Get Psych Meds, Less Likely to See Psychiatrists or Therapists
Seniors are twice as likely to receive psychotropic prescriptions than younger adults but are much less likely to receive mental health care from psychiatrists or to receive psychotherapy, according to a recent study published in the Journal of the American Geriatrics Society. "Our findings suggest that psychotropic medication use is widespread among older adults in outpatient care, at a far higher rate than among younger patients," the study’s lead author Dr. Maust said in a press release. “In many cases, especially for milder depression and anxiety, the safer treatment for older adults who are already taking multiple medications for other conditions might be more therapy-oriented, but very few older adults receive this sort of care."
Eli Lilly Defeats “Bellwether” Cymbalta Withdrawal Lawsuit
The Federal jury hearing the first of 5000 claims against Eli Lilly for hiding the risks of withdrawal symptoms associated with Cymbalta found that Lilly did not...
Lilly Faces First Week of “Bellwether” Cymbalta Withdrawal Lawsuit
Calling it “Poison,” plaintiff Claudia Herrera testified she would not have taken Eli Lilly's drug Cymbalta had she known the risks. Lilly hid the risks of...
Majority of Youth Prescribed Antipsychotics Have No Psychiatric Diagnosis
The majority of children, adolescents and young adults prescribed antipsychotic medications have not been diagnosed with a mental disorder, according to a recent study published in JAMA Psychiatry.
Controversial Exposure Therapy for PTSD Challenged
Research published in the May 2015 issue of The American Journal of Psychiatry questions the use of exposure therapy, the "gold standard" treatment for patients...
FDA: Antidepressant Trials Have Not Adequately Reported Sexual Dysfunction Side Effects
US Food and Drug Administration scientists want to better evaluate side effects of sexual dysfunction associated with antidepressant drugs.
Researcher: Antidepressants Protect Against Brain Shrinkage, Despite Our Findings
A Molecular Psychiatry study found that people who had recurrent depression developed smaller hippocampi and antidepressants protected against that effect -- except insofar as the study evidence seemed to show the opposite of what the media reported on it.
Many Physicians Don’t Understand Key Facts about Prescription Opioid Addictions
A Johns Hopkins Bloomberg School of Public Health survey of 1000 US primary care physicians found that many do not understand basic medical facts about the addictive nature of the opioids they are prescribing.
Antipsychotics Too Often Used to Dampen Aggression in Kids, Not Treat Psychosis
Antipsychotics appear to be too often prescribed to curb aggressive impulses in children and youth, rather than to treat psychosis or any other clinically indicated conditions.
Antidepressants Worsen Rapid Cycling in Bipolar Depression
-SSRI antidepressant medications contribute to a significant worsening of emotional "rapid cycling" in patients diagnosed with bipolar disorder.
Major Canadian Health Institute Calls For More Psychotherapy Instead of Drugs
An independent health research organization created to advise the Quebec government on best-evidence guidelines has called for psychotherapy to become the "front-line treatment choice in the mental-health system."
US House Committee Votes to Defund Agency for Healthcare Research & Quality
The primary agency responsible for investigating and reporting on the quality of health care delivery in the US is a step closer to being completely shut down.
Slew of New Studies Spot Links Between Psychiatric Medications and Bone Loss, Fractures
Four different studies conducted in different ways examining different groups have linked use of certain psychiatric drugs to bone fracture risks and negative impacts on human bone development.
Antidepressant-linked Suicide Data Doctored In Seminal Study
Several years after the information was first revealed, a published study has shown how an influential NIMH study doctored the real data about antidepressants and suicidal events in youth.







