The Increasing Placebo Response in Antipsychotic Drug Trials

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The American Journal of Psychiatry explores the implications for science and ethics of the rising placebo response rate in trials of antipsychotic drugs, in an...

J&J to Pay $2.2B to Settle Off-Label Risperdal Marketing Case

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Johnson & Johnson and its subsidiaries will pay more than $2.2 billion - one of the largest health-care fraud settlements in history - to...

“Persuasive” Evidence for Peer Support

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The Journal of Psychosocial Nursing reviews the evidence for peer support, finding "outcomes across a range of measures no different than when services had...

Higher Genetic Risk for Schizophrenia Linked to Lower Risk of Psychotic Experiences

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Research from the universities of Cardiff, Cambridge and Bristol finds no evidence of a link between genetic associations with schizophrenia and adolescent psychotic experiences....

Mood Instability Linked to Psychosis

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Research drawing on the British national survey finds that, despite the fact that psychotic conditions and mood disorders have historically been approached as separate...

Links Between Maternal Behavior and Psychological Sequelae

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Researchers from Taiwan and the United States find, in a study of 1,752 inner-city infants born between 1960 and 1965 (the Johns Hopkins Pathways...

Jury Awards $4M for Topamax Birth Defect

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After an hour of deliberation, jurors decided that the anticonvulsant Topamax (topiramate) had, in fact, caused April Czimmer's son to be born with a...

Louisiana Sues Pfizer Over Fraudulent Zoloft Marketing

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The Attorney General of Louisiana has filed suit against Pfizer, Inc. for concealing "serious issues" regarding Zoloft's efficacy. Citing a "deliberate, systematic practice" of...

Global Survey: Do Antidepressants Work?

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The Guardian and its partners in Europe - Le Monde, El Pais, La Stampa, Gazeta Wyborcza and Suddeutsche Zeitung - are conducting a global...

Early Life Stress Can Cause Adult PTSD, Even Without Memories

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Research from UCLA finds that rats exposed to early life trauma showed aberrations  of stress hormones, receptors in the amygdala, and inhibited or avoidant...

Sleep Sweeps Toxic Metabolites Out of the Brain

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Adding to our knowledge about the connection between sleep and mental health, researchers from the University of Rochester and N.Y.U. find that sleep creates...

The Upside of Sadness

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Being morose provides benefits, according to research suggesting that detail-oriented, analytical thinking styles can accompany periods of sadness.  Science News reports that people experiencing...

Traumatic Life Events, Not Genetics or Chemical Imbalance Cause Depression and Anxiety

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Researchers from three U.K. Universities analyzed the responses of 32,827 people to online questionnaires, finding that  social deprivation and traumatic or abusive life-experiences strongly...

State Of Mind Series Highlights Changes To Vermont Mental Health System

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Vermont Public Radio's series State of Mind will explore the ripples through Vermont's mental health system since Tropical Storm Irene washed away the State Hospital. In...

Schizophrenia as Stress-Induced Dopamine Supersensitivity

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Researchers from the University of Toronto departments of Psychiatry and Pharmacology, publishing in Progress in Neuro-Psychopharmacology and Biological Psychiatry, propose that various forms of stress,...

U.S. Antidepressant Sales Down: $9.4b From $12b Peak in 2008

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Antidepressants are still the most consumed class of medication in the U.S., with 270 million prescriptions per year. But sales revenue has gone down,...

Adderall Implicated in Michigan Murder Trial

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“This case does not make sense in the normal sense,” Assistant Prosecutor Doug Newton told jurors in the trial of Michael Hamilton for murder....

Postpartum Depression Crosses Generations

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Researchers at Tufts University exposed rats and their children to early life stress, resulting in depressed maternal care, aggression, increased restlessness and anxiety-related...

Risk of Bone Fractures With SSRIs Greater Than Thought

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Researchers from McMaster University's Department of Medicine, presenting at this year's American Society for Bone and Mineral Research's annual meeting, found that the magnitude...

Oxytocin for Autism, Schizophrenia?

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The September/October issue of the Harvard Review of Psychiatry reviews the biological and therapeutic research findings for the role of oxytocin in attachment, and...

Maternal Skin-to Skin Contact Affects Long-Term Development

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Israeli researchers find that maternal skin-to-skin contact with pre-term infants are related to "dynamic cascades of child physiological regulation and parental provisions in shaping...

Sinead O’Connor Announces: “I’m Not Bipolar . . . I Should Never Have Been...

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Singer Sinead O'Connor announced on her website that after several "second opinions" she has learned "I do not in fact suffer from Bi Polar...

Schizophrenia Neurotoxicity Redux

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Researchers in Spain and the U.K. find a similar pattern of brain volume changes in a group 76 controls and 109 patients with schizophrenia...

Most Clinical Trials Don’t Report Results

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An article in PLoS One, by researchers at the National Institute of Health in Bethesda, Maryland, finds that less than half (45%) of clinical...

Psych Meds Found in the Home of Woman Killed in D.C. Car Chase

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Miriam Carey, who was shot and killed yesterday by D.C. police after she attempted to drive through a White House barricade with her 1-year-old...